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In confirming specificity of the knock down studies, co-transfection of cells with siKRASG12V and constitutively active KRAS or RAF1 (Figure 2D and S3) restored In contrast, constructs bearing mutations in known PKA-dependent phosphorylation sites (Taurin et al., 2006) (552 and 675) effectively accumulated in the

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In confirming specificity of the knock down studies, co-transfection of cells with siKRASG12V and constitutively active KRAS or RAF1 (Figure 2D and S3) restored In contrast, constructs bearing mutations in known PKA-dependent phosphorylation sites (Taurin et al., 2006) (552 and 675) effectively accumulated in the

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